OK, let me re-phrase. If you haven't suggested the site in the last, say, nine months, then one more suggestion won't irritate an editor, and might conceivably help an editor. If you've suggested it in that time, then there's no point in a resubmittal.
Site optimization has nothing to do with an ODP listing. It's all about content. As for site design, if a surfer can effectively use the site and quickly find its unique content, then an ODP editor can review it. I've (happily) listed some sites that I thought were horrible website designs. But the content!
I'd say that "every website is personal" -- and so the unique content always boils down to answers to a few basic questions: "who are you? what do you know? what happened to you? what have you done, and what would you do for money?"
This may be a slight exaggeration. But look at even the heavily-spammed categories: the worthwhile travel sites are by people who've traveled to the places described; the worthwhile nutrition sites are by people who have either professional degrees or long-standing, carefully-recorded personal experience; the worthwhile real-estate sites are by people with years of experience in the business; the worthwhile loan sites are from banks or credit unions or established consumer-protection organizations--all drawing on that personal knowledge and experience.
So, provided you've experienced something people might want to hear about, or you've described it in a way people might want to hear, that would count as significant content, and that's almost(*) the ONLY kind of significant content.
OK, almost. Much of what I've prepared for web publication isn't, perhaps, MY experience -- it was previously published on dead tree pulp. But I chose people who had done something new, unique, and significant, but who weren't yet represented online (such as Isaac Watts, Catherine Winkworth, J. M. Neale, etc.), and let THEIR personality speak in THEIR own words. It's my web development work, but in a very real sense THEIR personal websites. And there's still a lot of significant people whose personal work isn't yet online!